Search results for "design [accelerator]"
showing 10 items of 594 documents
Designed for unanticipated use
2003
Common artefacts have been identified as fundamental characteristics for framing activities in workplaces. Mike Robinson's article 'Design for unanticipated use...' conceptualised and defined the dimensions of common artefacts as consisting of predictability, peripheral awareness, implicit communication, double level language and overview. These dimensions have often been used in explaining unexpected uses of different applications and systems. In this paper, experiences from common artefacts as CSCW application design principles, indicating that unanticipated uses are expected and further supported, are discussed. Two distinct cases, a physical room and a software application, are presente…
Soil Bioengineering in peri-urban Mediterranean areas, an international educational project developed by AIPIN Sicily, APENA, University of Palermo a…
2014
Soil Bioengineering applied to landscape architecture in urban and periurban areas characterized by mediterranean climate is a project funded by Italian MIUR within the program Messaggeri della Conoscenza. It aims to promote experimental initiatives in teaching and research in academic centers of excellence. The project is divided into 3 phases: didactic activity at the University of Palermo, internship at the Institute Superior de Agronomia of the University of Lisbon; dissemination activities of take home messages learned during the exchange period. During the first phase, more than 20 participants made three project proposals to achieve a practice construction exercises. The best five pa…
A statistical design of experiments for optimizing the MALDI-TOF-MS sample preparation of polymers. An application in the assessment of the thermo-me…
2011
[EN] The sample preparation procedure for MALDI-TOF MS of polymers is addressed in this study by the application of a statistical Design of Experiments (DoE). Industrial poly (ethylene terephthalate) (PET) was chosen as model polymer. Different experimental settings (levels) for matrixes, analyte/matrix proportions and concentrations of cationization agent were considered. The quality parameters used for the analysis were signal-to-noise ratio and resolution. A closer inspection of the statistical results provided the study not only with the best combination of factors for the MALDI sample preparation, but also with a better understanding of the influence of the different factors, individua…
Assessing the MALDI-TOF MS sample preparation procedure to analyze the influence of thermo-oxidative ageing and thermo-mechanical degradation on poly…
2011
[EN] Multiple processing by means of successive injection cycles was used to simulate the thermo-mechanical degradation effects on the oligomeric distribution of PLA under mechanical recycling. Likewise, an accelerated thermal ageing over PLA glass transition was performed in order to simulate its service life. MALDI-TOF MS was used for the analysis and the sample preparation procedure was assessed by means of a statistical Design of Experiments (DoE). The quality effects in use for the analysis were signal-to-noise ratio and Resolution. Different matrixes, analyte/matrix proportions and the use of NaTFA as cationization agent were considered. A deep inspection of the statistical results pr…
X-ray irradiation effects on fluorine-doped germanosilicate optical fibers
2014
International audience; We report an experimental investigation on the effects of fluorine codoping on the radiation response of Ge-doped Optical Fibers (OFs) obtained by three different drawing conditions. The OFs were irradiated with 10 keV X-rays up to 300 Mrad and studied by online Radiation-Induced-Attenuation (RIA) measurements. Confocal Micro- Luminescence (CML) and Electron Paramagnetic Resonance (EPR) were also employed to investigate the permanent radiation-induced-defects. The variation of the Germanium-Lone-Pair-Center (GLPC) and Non-Bridging- Oxygen-Hole-Centers (NBOHC) concentration with the radiation dose is investigated by CML, whereas the ones of the induced Ge(1), Ge(2) an…
Applications of the vehicle routing problem with trailers and transshipments
2013
Abstract The vehicle routing problem with trailers and transshipments (VRPTT) is a recent and challenging extension of the well-known vehicle routing problem. The VRPTT constitutes an archetypal representative of the class of vehicle routing problems with multiple synchronization constraints (VRPMSs). In addition to the usual task covering constraints, VRPMSs require further synchronization between vehicles, concerning spatial, temporal, and load aspects. VRPMSs possess considerable practical relevance, but limited coverage in the scientific literature. The purpose of the present paper is to describe how several important types of VRPMSs, such as multi-echelon location-routing problems and …
A new mathematical approach for the estimation of the AUC and its variability under different experimental designs in preclinical studies
2011
The aim of the present work was to develop a new mathematical method for estimating the area under the curve (AUC) and its variability that could be applied in different preclinical experimental designs and amenable to be implemented in standard calculation worksheets. In order to assess the usefulness of the new approach, different experimental scenarios were studied and the results were compared with those obtained with commonly used software: WinNonlin® and Phoenix WinNonlin®. The results do not show statistical differences among the AUC values obtained by both procedures, but the new method appears to be a better estimator of the AUC standard error, measured as the coverage of 95% confi…
Latin hypercube sampling with inequality constraints
2010
International audience; In some studies requiring predictive and CPU-time consuming numerical models, the sampling design of the model input variables has to be chosen with caution. For this purpose, Latin hypercube sampling has a long history and has shown its robustness capabilities. In this paper we propose and discuss a new algorithm to build a Latin hypercube sample (LHS) taking into account inequality constraints between the sampled variables. This technique, called constrained Latin hypercube sampling (cLHS), consists in doing permutations on an initial LHS to honor the desired monotonic constraints. The relevance of this approach is shown on a real example concerning the numerical w…
Lattices and dual lattices in optimal experimental design for Fourier models
1998
Number-theoretic lattices, used in integration theory, are studied from the viewpoint of the design and analysis of experiments. For certain Fourier regression models lattices are optimal as experimental designs because they produce orthogonal information matrices. When the Fourier model is restricted, that is a special subset of the full factorial (cross-spectral) model is used, there is a difficult inversion problem to find generators for an optimal design for the given model. Asymptotic results are derived for certain models as the dimension of the space goes to infinity. These can be thought of as a complexity theory connecting designs and models or as special type of Nyquist sampling t…
Estimating Mean Lifetime from Partially Observed Events in Nuclear Physics
2022
Abstract The mean lifetime is an important characteristic of particles to be identified in nuclear physics. State-of-the-art particle detectors can identify the arrivals of single radioactive nuclei as well as their subsequent radioactive decays (departures). Challenges arise when the arrivals and departures are unmatched and the departures are only partially observed. An inefficient solution is to run experiments where the arrival rate is set very low to allow for the matching of arrivals and departures. We propose an estimation method that works for a wide range of arrival rates. The method combines an initial estimator and a numerical bias correction technique. Simulations and examples b…